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48 hours. In May 2005, the U.S. Food and Drug Administration found that tadalafil (along with other PDE5 inhibitors) could lead to vision impairment in certain patient groups, including diabetics. An investigation is currently ongoing. edit Drug interactions — organic nitrates Since PDE5 inhibitors such as tadalafil may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of tadalafil. Using organic nitrates (such as the sex drug Amyl nitrite) within this timeframe may increase the risk of life-threatening hypotension. Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (GTN Spray), these patients should seek immediate medical attention if they experience anginal chest pain 1 . In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil. edit Marketing In the United States, Eli Lilly has a multiyear agreement to promote tadalafil (Cialis) with professional golf's PGA TOUR. edit Trivia Some individuals with the surname of "Cialis" objected to the naming of Lilly's drug, but the pharmaceutical giant insists that the drug's name has nothing to do with the surname. 2 edit Cialis drug history This article or section does not cite its references or sources. Please help improve this article by introducing appropriate citations. (help, get involved!) This article has been tagged since October 2006. This article or section may require cleanup to meet Wikipedia's quality standards | Xanax info | Xanax use | Alprazolam generic xanax | Free xanax | Pharmacy xanax | Xanax detox | Snorting xanax | [ Phentermine ]