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Ons & 149 Side EffectComparisons & 149 Health Conditions & 149 Treatment Options & 149 Care Paths & 149 Check for Savings & 149 Health RiskAssessments & 149 Medication Card & 149 Medication Checklist Search Drugs & Herbs Conditions News & Reviews Drug Comparisons Selective Serotonin Reuptake Inhibitors Depression can occur if some of the chemicals in your brain are not functioning effectively. There are three specific chemicals that can affect your mood: serotonin (also known as 5-HT), norepinephrine (NE), or dopamine (DA). Specifically, serotonin acts as a chemical messenger in the brain. Its job is to pass signals from one nerve ending to the next. Once it delivers its signal or message, serotonin is taken up by the nerve tissue and broken down for the brain and body to reuse. If serotonin levels are low, it is difficult for nerve endings in the brain to communicate well with each other. Abnormally low levels of serotonin may not only play a role in diseases such as depression but also in conditions like panic disorder, obsessive compulsive disorder, social anxiety disorder, and eating disorders. The selective serotonin reuptake inhibitors (SSRIs) block the ability of the nerve endings to bind and break down serotonin so that more serotonin is available to help the brain process nerves messages more efficiently and correctly. Drugs in this Class Citalopram (Celexa) Citalopram Oral Solution (Celexa Solution) Escitalopram (Lexapro) Fluoxetine Oral Solution (Prozac Oral Solution) Fluoxetine tablets or capsules (Prozac) Fluvoxamine (Luvox) Paroxetine (Paxil, Paxil CR) Paroxet | Paxil paroxetine | Paxil alcohol interaction | Paxil cr canada | Paxil effexor withdrawal | Paxil online | Paxil cr | Buy paxil | [ Phentermine ]