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Paxil. E tricyclic or tetracyclic antidepressants. In receptor binding studies, paroxetine did not exhibit significant affinity for the adrenergic (α1, α2, β), dopaminergic, serotonergic (5HT1, 5HT2), or histamine receptors of rat brain membrane. A weak affinity for the muscarinic acetylcholine and noradrenaline receptors was evident. The predominant metabolites of paroxetine are essentially inactive as 5-HT reuptake inhibitors. edit Paroxetine controlled release (CR) Paroxetine controlled release contains a Geomatrix™ tablet that controls the absorption of the drug. Clinical studies show that controlled release tablet provides effective symptom relief with a lower number of patients stopping their treatment due to side effects. 10 However, the need for an extended release form of paroxetine has not been established, as the FDA indicated that the half-life for the original Paxil was ideal for once-daily dosing, and that a CR version was not needed. edit Chemistry Paroxetine hydrochloride paxil

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is an odorless, off-white powder, having a melting point range of 120° to 138°C and a solubility of 5.4 mg mL in water. edit Formulations Paxil Seroxat (paroxetine) is available in 10, 20, 30, and 40 mg tablets. Paxil CR (paroxetine extended release) is available in 12.5, 25, and 37.5 mg tablets. Paxil, Seroxat and Paxil CR are manufactured by GlaxoSmithKline, however a generic is now available under the chemical name paroxetine. edit Side effects General side effects are mostly present during the first 1-4 weeks while the body adapts to the drug. Almost all SSRIs are known to cause either one or more of these symptoms. A person receiving paroxetine treatment may experience a few, all, or none of the following side-effects, and most side-effects will disappear or lessen with continued treatment, though some may last throughout the duration. Nausea Teratogenicity: Pregnant women are advised not to take the drug due to possible fetal heart defects. 11 Drowsiness Headache Changes in we paxil

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paxil Ic daily headache". Headache 34 (10): 587-589. PMID 7843954. ^ Sindrup SH paxil, Gram LF paxil, Brosen K paxil, Eshoj O paxil, Mogensen EF (2002). "A randomized trial comparing paroxetine and venlafaxine in the treatment of bipolar depressed patients taking mood stabilizers". Journal of Clinical Psychiatry 63 (6): 508-512. PMID 12088162. ^ Vieta E paxil, Martinez-Aran A paxil, Goikolea JM paxil, Torrent C paxil, Colom F paxil, Benabarre A paxil, Reinares M (1999). "The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms". Pain 42 (2): 135-144. PMID 2147235. ^ Kim SW paxil, Grant JE paxil, Adson DE paxil, Shin YC paxil, Zaninelli R (2002). "A double-blind placebo-controlled study of paxil.

paxil the efficacy and safety of paroxetine in the treatment of pathological gambling". Journal of Clinical Psychiatry 63 (6): 501-507. PMID 12088161. ^ Weitzner MA paxil, Moncello J paxil, Jacobsen PB paxil, Minton S. (2002). "A pilot trial of paroxetine for the treatment of hot flashes and associated symptoms in women with breast cancer.". Journal of Pain and Symptom Management 23 (4): 337-345. PMID 11997203. ^ Golden RN paxil, Nemeroff CB paxil, McSorley P paxil, Pitts CD paxil, Dube EM. (2002). "Efficacy and tolerability of controlled-release and immediate-release paroxetine in the treatment of depression.". Journal of Clinical Psychiatry 63 (7): 577-584. PMID 12143913. ^ FDA Warning on Birth defects ^ Clayton A paxil, Keller A paxil, McGarvey EL. Burden of phase-specific sexual dysfunction with SSRIs. J Affect Disord 2006;91:27-32. PMID 16430968. ^ Haddad P (2001). "Antidepressant discontinuation syndromes". Drug Saf 24 (3): 183-97. PMID 11347722. ^ Quitpaxil.org - Information for persons suffering from Paxil withdrawal syndrome ^ Yerevanian B paxil, Koek R paxil, Feusner J paxil, Hwang S paxil, Mintz J (2004). "Antidepressants and suicidal behaviour in unipolar depression". Acta Psychiatr Scand 110 (6): 452-8. PMID 15521830. ^ http: www.ncbi.nlm.nih.gov entrez query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17138801&query_hl=2&itool=pubmed_docsum PMID = .

paxil ^ Clayton A paxil, Keller A paxil, McGarvey EL. Burden of phase-specific sexual dysfunction with SSRIs. J Affect Disord 2006;91:27-32. PMID 16430968. ^ Haddad P (2001). "Antidepressant discontinuation syndromes". Drug Saf 24 (3): 183-97. PMID 11347722. ^ Quitpaxil.org - Information for persons suffering from Paxil withdrawal syndrome ^ Yerevanian B paxil, Koek R paxil, Feusner J paxil, Hwang S paxil, Mintz J (2004). "Antidepressants and suicidal behaviour in unipolar depression". Acta Psychiatr Scand 110 (6): 452-8. PMID 15521830. ^ http: www.ncbi.nlm.nih.gov entrez query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17138801&query_hl=2&itool=pubmed_docsum PMID = 1.

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* header h1 h2.date-header .date-header span .sidebar h2 .sidebar .Profile h2 .post h3 .post h3 a, .post h3 a:visited comments h4 * text ----------------------------------------------- * header h1 header .description .post-body p .post-footer .uncustomized-post-template .post-footer .uncustomized-post-template .post-footer .post-author, .uncustomized-post-template .post-footer .post-timestamp p.comment-author .deleted-comment .comment-body p .feed-links footer .widget * lists ----------------------------------------------- * .post ul .post li comments ul comments li .sidebar ul .sidebar li blog-pager-newer-link blog-pager-older-link blog-pager * links ----------------------------------------------- * a a:hover a.comment-link html>body a.comment-link .sidebar a .sidebar a:hover header h1 a header h1 a:hover .post h3 a a img .clear .profile-textblock .profile-img .profile-link ** Page structure tweaks for layout editor wireframe * body layout main, body layout sidebar @import url('http: www2.blogger.com css blog_controls.css'); @import url('http: www2.blogger.com dyn-css authorization.css?blogID=3346125413688676171'); skip to main skip to sidebar Paxil Buy Online Paxil information from paxil-buy-online.blogspot.com, includes Paxil side effects interactions, indications. Wednesday, December 20, 2006 Paxil Paxil a phenylpiperidine antidepressants that inhibits the reuptake of Serotonin ( SSRI ) This drug is used in the treatment of OCD ( obsessive-compulsive disorder ) but is also used to relief symptoms of depression, diabetic nerve pain ( neuropathy ) ,panic attacks disorder,

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