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Vioxx bextra celebrex. Harsh Criticism From WithinScientist Says Regulation Of Drugs Is Inadequate For Patient SafetyArthritis Drugs Under ReviewNew Drug-Monitoring Board Announced As Painkiller Panel Set To Meet Spotlight On Painkiller SafetySenay On FDA Look At Controversial Arthritis DrugsGov't OKs Vioxx, Celebrex, BextraDespite Heart Risks, Advisors Say Drugs Should Stay On MarketWASHINGTON, Feb. 18, 2005QuoteCommittee members noted that Celebrex seems to have the least heart side effect of the three drugs, though some complained about the lack of needed data. (CBS AP) A Food and Drug Administration advisory panel narrowly voted Friday to recommend that Merck & Co. be allowed to resume sales of its painkiller Vioxx, which the company removed from the market last year because it increased patients' risk of cardiovascular problems. The panel said that all three scrutinized Cox-2 drugs — Bextra, Celebrex and Vioxx — pose cardiovascular risks, but still voted 17-15 to keep Vioxx on the market. The news sent vioxx bextra
 

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Merck shares skyrocketing. The decision, which surprised many analysts, came the same day that the panel voted to recommend allowing both of Pfizer Inc.'s painkillers Celebrex and Bextra to remain on the market, as long as Celebrex has a stronger warning label, CBS News Medical Correspondent Elizabeth Kaledin reports. The one thing panel members almost unanimously agreed on is that these drugs must be used under the strictest warnings and tightest supervision, pushing for black box warning labels that let the people know that these drugs can help but can't be taken lightly, Kaledin reported. The vote for Bextra was 17-13 with two abstaining. While the Vioxx decision was the closest, 17-15, Celebrex passed the panel's approval easily, 31-1. Merck spokesman Christopher Loder said the company looked forward to discussing the issue with the FDA. The FDA typically follows the recommendations of its advisory panels, but it was unclear Friday what Merck would need to do to resume selling the vioxx bextra


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vioxx bextra celebrex Articular vioxx bextra celebrex, from prominent critics. FDA whistleblower Dr. David Graham said: "there doesn't appear to be a need for Cox-2" inhibitors. Graham authored a study published in Lancet vioxx bextra celebrex, which said Vioxx caused an estimated 88 vioxx bextra celebrex, 000 to 140 vioxx bextra celebrex, 000 excess cases of serious heart disease in the U.S. while it was on the market. Meanwhile vioxx bextra celebrex, meeting chairman Alistair J. J. Wood of Vanderbilt University Medical School said vioxx bextra celebrex, "The data are very compelling vioxx bextra celebrex, Vioxx is substantially worse than the others." Last year vioxx bextra celebrex, Celebrex sales leapt 75 percent to $3.3 billion. In December vioxx bextra celebrex, during the week when word of its cardiovascular risk became public vioxx bextra celebrex, Celebrex claimed 44 percent of prescripti vioxx bextra celebrex.

vioxx bextra celebrex On pain killer sales in the retail market with revenues of $44 million. By the week ended Feb. 11 vioxx bextra celebrex, Celebrex's share fell to 23 percent with sales of $24 million vioxx bextra celebrex, according to Verispan vioxx bextra celebrex, which tracks prescription drug information. In trading Friday vioxx bextra celebrex, Merck shares surged $3.76 vioxx bextra celebrex, or 13 percent vioxx bextra celebrex, to close at $32.61 on the New York Stock Exchange vioxx bextra celebrex, while Pfizer shares gained $1.74 vioxx bextra celebrex, or 6.9 percent vioxx bextra celebrex, to finish at $26.80. Bert Hazlett vioxx bextra celebrex, an analyst at SunTrust Robinson Humphrey vioxx bextra celebrex, upgraded Merck to a buy from a neutral because he believes Vioxx will return to the market for use in a limited population. And while Vioxx sales my be relatively small vioxx bextra celebrex, he predicted the resurrection of the drug may help limit the company's legal liability. Hundreds of lawsuits have been filed against Merck over Vioxx and some have estimated the company's liability could go to $30 billion. "I wouldn't want to be a plaintiff's lawyer right now vioxx bextra celebrex, " said Hazlett. While the warning could further dampen Celebrex sales vioxx bextra celebrex, analysts don't think it will be extreme. "Celebrex will still be a blockbuster vioxx bextra celebrex, " said Hazlett. © MMV vioxx bextra celebrex, CBS Broadcasting Inc. All Rights Reserved. This material may not be published vioxx bextra celebrex, broadcast vioxx bextra celebrex, rewritten vioxx bextra celebrex, or redistributed. The Associated Press contributed to this report.INSIDE HealthAccountability Plagues Bush AIDS ProgramReport: Success Of AIDS E.

vioxx bextra celebrex of the drug may help limit the company's legal liability. Hundreds of lawsuits have been filed against Merck over Vioxx and some have estimated the company's liability could go to $30 billion. "I wouldn't want to be a plaintiff's lawyer right now vioxx bextra celebrex, " said Hazlett. While the warning could further dampen Celebrex sales vioxx bextra celebrex, analysts don't think it will be extreme. "Celebrex will still be a blockbuster vioxx bextra celebrex, " said Hazlett. © MMV vioxx bextra celebrex, CBS Broadcasting Inc. All Rights Reserved. This material may not be published vioxx bextra celebrex, broadcast vioxx bextra celebrex, rewritten vioxx bextra celebrex, or redistributed. The Associated Press contributed to this report.INSIDE HealthAccountability Plagues Bush AIDS ProgramReport: Success Of AIDS Ef.

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Life Recreation Technology Travel Shopping Odds & Ends Top Writers Write For Us PRINT FULL TEXT PAGES: 1 2 Vioxx, Bextra, Celebrex and Cancer by Sandra Bell July 06, 2005 A little background Vioxx, Bextra, and Celebrex are NAIDs (Non-steroidal anti-inflammatory drugs). They are also called cox 2 inhibitors and were developed to treat arthritis. The older NAISDs like aspirin, ibuprofen, and naproxin worked just as well but they were cox 1 and cox 2 inhibitors and, over time, could cause stomach irritation, bleeding, and ulcers. All these drugs block the cox 2 enzyme when there is inflammation. The cox 2 enzyme is also produced by pre- cancerous tissues. But cox 2 also plays an important part in controlling the cardiovascular system--stopping platelets from forming thrombi and preventing damage to blood vessels. Vioxx was voluntarily withdrawn and in April 2005 the FDA required Bextra to be taken off the market. It seems likely that Celebrex will meet the same fate. There are lawsuits pending against the makers of all three drugs. The cox 2 inhibitors and cancer research Ironically, the cox 2 inhibitors have shown great promise in preventing or slowing the growth of cancer. Researchers at Jefferson Medical College have shown that elevated levels of cox 2 were found in breast cancers. The Journal of the Canadian Opthalmology Society reported that researchers found high levels of cox 2 in uveal melanoma and that cox 2 inhibitors could prevent this. At the University of North Carolina, research indicated that Celebrex slowed the growth of prostate cancers. By 2004 the NCI (Natio

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