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G that mark the disorder. The study, published in the International Journal of Eating Disorders, received partial funding from Zoloft maker Pfizer, Inc. People with bulimia, most often young women, go through repeated episodes of binge-eating followed by purging, through vomiting or abuse of laxatives; some fast or excessively exercise to counter the binge. Treatment typically involves counseling to address the distorted body image and other destructive thoughts and feelings that underlie the disorder. The antidepressant Prozac, which was approved in the U.S. in 1996 to treat bulimia, is another treatment option. Like that drug, Zoloft -- known generically as sertraline -- is a selective serotonin reuptake inhibitor, or SSRI, but it has not received much attention as a potential bulimia therapy, according to the authors of the new study. They found that after eight weeks on Zoloft, only two of the 14 women who completed the study remained above the threshold for probable bulimia, as did the four women who dropped out before completing treatment. Half of those who finished the study had stopped bingeing and purging by the end. The most common side effects of the drug were diarrhea, headache, jitteriness and nausea. Despite the drop in symptoms, the study does not prove Zoloft was effective for these patients because there was no comparison group that got a placebo, or inactive treatment. All of the women knew they were receiving the antidepressant, so the improvement in their symptoms may have been the result of their expectations that they would get better, lead study autho
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