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Cr gain paxil weight. were: Abnormal ejaculation, somnolence, impotence, libido decreased, tremor, sweating, and female genital disorders (generally anorgasmia or difficulty achieving orgasm). Social Anxiety Disorder: In the social anxiety disorder study, the adverse events meeting these criteria were: Nausea, asthenia, abnormal ejaculation, sweating, somnolence, impotence, insomnia, and libido decreased. Premenstrual Dysphoric Disorder: The most commonly observed adverse events associated with the use of PAXIL CR either during continuous dosing or luteal phase dosing (incidence of 5% or greater and incidence for PAXIL CR at least twice that for placebo, derived from Table 5) were: Nausea, asthenia, libido decreased, somnolence, insomnia, female genital disorders, sweating, dizziness, diarrhea, and constipation. In the luteal phase dosing PMDD trial, which employed dosing of 12.5 mg day or 25 mg day of PAXIL CR limited to the 2 weeks prior to the onset of menses over 3 consecutive menstrual cycles, adverse cr gain
 

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events were evaluated during the first 14 days of each off-drug phase. When the 3 off-drug phases were combined, the following adverse events were reported at an incidence of 2% or greater for PAXIL CR and were at least twice the rate of that reported for placebo: Infection (5.3% versus 2.5%), depression (2.8% versus 0.8%), insomnia (2.4% versus 0.8%), sinusitis (2.4% versus 0%), and asthenia (2.0% versus 0.8%). Incidence in Controlled Clinical Trials: Table 1 enumerates adverse events that occurred at an incidence of 1% or more among patients treated with PAXIL CR, aged 18 to 65, who participated in 2 short-term (12-week) placebo-controlled trials in major depressive disorder in which patients were dosed in a range of 25 mg to 62.5 mg day. Table 2 enumerates adverse events reported at an incidence of 5% or greater among elderly patients (ages 60 to 88) treated with PAXIL CR who participated in a short-term (12-week) placebo-controlled trial in major depressive disorder in which patie cr gain


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cr gain paxil weight Ere patient characteristics and other factors differ from those that prevailed in the clinical trials. Similarly cr gain paxil weight, the cited frequencies cannot be compared with figures obtained from other clinical investigations involving different treatments cr gain paxil weight, uses cr gain paxil weight, and investigators. The cited figures cr gain paxil weight, however cr gain paxil weight, do provide the prescribing physician with some basis for estimating the relative contribution of drug and nondrug factors to the side effect incidence rate in the population studied. Table 1. Treatment-Emergent Adverse Events Occurring in & 179; 1% of Patients Treated With PAXIL CR in a Pool of 2 Studies in Major Depressive Disorder1 cr gain paxil weight, 2 Body System Adverse Event % Rep cr gain paxil weight.

cr gain paxil weight Orting Event PAXIL CR (n = 212) Placebo (n = 211) Body as a Whole Headache 27% 20% Asthenia 14% 9% Infection3 8% 5% Abdominal Pain 7% 4% Back Pain 5% 3% Trauma4 5% 1% Pain5 3% 1% Allergic Reaction6 2% 1% Cardiovascular System Tachycardia 1% 0% Vasodilatation7 2% 0% Digestive System Nausea 22% 10% Diarrhea 18% 7% Dry Mouth 15% 8% Constipation 10% 4% Flatulence 6% 4% Decreased Appetite 4% 2% Vomiting 2% 1% Nervous System Somnolence 22% 8% Insomnia 17% 9% Dizziness 14% 4% Libido Decreased 7% 3% Tremor 7% 1% Hypertonia 3% 1% Paresthesia 3% 1% Agitation 2% 1% Confusion 1% 0% Respiratory System Yawn 5% 0% Rhinitis 4% 1% Cough Increased 2% 1% Bronchitis 1% 0% Skin and Appendages Sweating 6% 2% Photosensitivity 2% 0% Special Senses Abnormal Vision8 5% 1% Taste Perversion 2% 0% Urogenital System Abnormal Ejaculation9 cr gain paxil weight, 10 26% 1% Female Genital Disorder9 cr gain paxil weight, 11 10% <1% Impotence9 5% 3% Urinary Tract Infection 3% 1% Menstrual Disorder9 2% <1% Vaginitis9 2% 0% 1.Adverse events for which the PAXIL CR reporting incidence was less than or equal to the placebo incidence are not included. These events are: Abnormal dreams cr gain paxil weight, anxiety cr gain paxil weight, arthralgia cr gain paxil weight, depersonalization cr gain paxil weight, dysmenorrhea cr gain paxil weight, dyspepsia cr gain paxil weight, hyperkinesia cr gain paxil weight, increased appetite cr gain paxil weight, myalgia cr gain paxil weight, nervousness cr gain paxil weight, pharyngitis cr gain paxil weight, purpura cr gain paxil weight, rash cr gain paxil weight, respiratory disorder cr gain paxil weight, sinusitis cr gain paxil weight, urinary frequency cr gain paxil weight, and weig.

cr gain paxil weight Nd Appendages Sweating 6% 2% Photosensitivity 2% 0% Special Senses Abnormal Vision8 5% 1% Taste Perversion 2% 0% Urogenital System Abnormal Ejaculation9 cr gain paxil weight, 10 26% 1% Female Genital Disorder9 cr gain paxil weight, 11 10% <1% Impotence9 5% 3% Urinary Tract Infection 3% 1% Menstrual Disorder9 2% <1% Vaginitis9 2% 0% 1.Adverse events for which the PAXIL CR reporting incidence was less than or equal to the placebo incidence are not included. These events are: Abnormal dreams cr gain paxil weight, anxiety cr gain paxil weight, arthralgia cr gain paxil weight, depersonalization cr gain paxil weight, dysmenorrhea cr gain paxil weight, dyspepsia cr gain paxil weight, hyperkinesia cr gain paxil weight, increased appetite cr gain paxil weight, myalgia cr gain paxil weight, nervousness cr gain paxil weight, pharyngitis cr gain paxil weight, purpura cr gain paxil weight, rash cr gain paxil weight, respiratory disorder cr gain paxil weight, sinusitis cr gain paxil weight, urinary frequency cr gain paxil weight, and weigh.

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