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was conducted to compare Lexapro and Paxil ® (paroxetine HCL) in the treatment of GAD. In this trial, patients taking Lexapro and patients taking Paxil® experienced improvement of their GAD symptoms. However, fewer patients stopped taking Lexapro due to side effects as compared to patients taking Paxil® (7% for Lexapro vs 23% for Paxil®).7 In addition, in this trial, clinically significant weight gain occurred less often in patients treated with Lexapro over 24 weeks (8% for Lexapro vs 18% for Paxil®).7 References: 1. Burke WJ, Gergel I, Bose A. Fixed-dosed trial of the single isomer SSRI escitalopram in depressed outpatients. J Clin Psychiatry. 2002;63:331-336. 2. Data on file, Forest Laboratories, Inc. 3. Montgomery SA, Huusom AKT, Bothmer J. Escitalopram is at least as effective as venlafaxine XR in the treatment of depression and is better tolerated. Poster presented at: 15th ECNP Congress; October 5–9, 2002; Barcelona, Spain. 4. Zimbroff DL, Bose A, Li D. Escitalopram treatment of SSRI non-responders can lead to remission in patients who fail initial SSRI therapy. Poster presented at: 157th Annual Meeting of the American Psychiatric Association; May 1-6, 2004; New York, NY. 5. Goodman WK, Bose A. Wang Q. Poster presented at: 23rd Annual Conference of the Anxiety Disorders Association of America, 2003; 6. Lexapro package insert . St Louis, MO: Forest Pharmaceuticals, Inc.; 2004. 7. Bielski RJ, Bose A, Chang C, Keller MB. A double-blind comparison of escitalopram and paroxetine in the long-term treatment of generalized anxiety disorder. Poster presented at: Am
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